Karyne,
If you want some references on the forensic detection of growth promoting
drugs using stable isotopes:
Southan, G., Mallet, A., Jumeau, J., Craig, S., Poojarra, N., Mitchell, D.,
Wheeler, M. and Brooks, R. V. (1990) Proceedings and Abstracts of the Second
International Symposium on Applied Mass Spectrometry, Barcelona, Spain, 306.
Becchi M., Aguilera R., Farizon Y., Flament M. M., Casabianca H., and James
P. (1994) Gas-Chromatography Combustion Isotope Ratio Mass-Spectrometry
Analysis of Urinary Steroids to Detect Misuse of Testosterone in Sport.
Rapid Communications in Mass Spectrometry 8(4), 304-308.
Aguilera R., Becchi M., Grenot C., Casabianca H., and Hatton C. K. (1996)
Detection of testosterone misuse: Comparison of two chromatographic sample
preparation methods for gas chromatographic-combustion/isotope ratio mass
spectrometric analysis. Journal of Chromatography B 687(1), 43-53.
Aguilera R., Becchi M., Grenot C., Casabianca H., and Hatton C. K. (1996)
Detection of testosterone misuse: Comparison of two chromatographic sample
preparation methods for gas chromatographic-combustion/isotope ratio mass
spectrometric analysis. Journal of Chromatography B 687(1), 43-53.
Shackleton C. H. L., Phillips A., Chang T., and Li Y. (1997) Confirming
testosterone administration by isotope ratio mass spectrometric analysis of
urinary androstanediols. Steroids 62(4), 379-387.
Shackleton C. H. L., Roitman E., Phillips A., and Chang T. (1997)
Androstanediol and 5-androstenediol profiling for detecting exogenously
administered dihydrotestosterone, epitestosterone, and
dehydroepiandrosterone: Potential use in gas chromatography isotope ratio
mass spectrometry. Steroids 62(10), 665-673.
Aguilera R., Becchi M., Mateus L., Popot M. A., Bonnaire Y., Casabianca H.,
and Hatton C. K. (1997) Detection of exogenous hydrocortisone in horse urine
by gas chromatography combustion carbon isotope ratio mass spectrometry.
Journal of Chromatography B 702(1-2), 85-91.
Horning S., Geyer H., Machnik M., Schanzer W., Hilkert A., and Oesselmann J.
(1997) Detection of exogenous testosterone by 13C/12C analysis. Recent
Advances in Doping Analysis (4): Proceedings of the 14th Cologne Workshop on
Dope Analysis, 275-283.
Mason P. M., Hall S. E., Gilmour I., Houghton E., Pillinger C., and Seymour
M. A. (1998) The use of stable carbon isotope analysis to detect the abuse
of testosterone in cattle. Analyst 123(12), 2405-2408.
Ferchaud V., LeBizec B., Monteau F., and Andre F. (1998) Determination of
the exogenous character of testosterone in bovine urine by gas
chromatography-combustion-isotope ratio mass spectrometry. Analyst 123(12),
2617-2620.
Horning S., Geyer H., Flenker U., and Schanzer W. (1998) Detection of
exogenous steroids by 13C/12C analysis. Recent Advances in Doping Analysis
(5): Proceedings of the 15th Cologne Workshop on Dope Analysis, 135-148.
Aguilera R., Catlin D. H., Becchi M., Phillips A., Wang C., Swerdloff R. S.,
Pope H. G., and Hatton C. K. (1999) Screening urine for exogenous
testosterone by isotope ratio mass spectrometric analysis of one
pregnanediol and two androstanediols. Journal of Chromatography B 727(1-2),
95-105.
Wolthers B. G. and Kraan G. P. B. (1999) Clinical applications of gas
chromatography and gas chromatography- mass spectrometry of steroids.
Journal of Chromatography A 843(1-2), 247-274.
Houghton E., Ginn A., Hall S. E., Horning S., Mason P., Gilmour I.,
Pillinger C., Seymour M. A., and Schanzer W. (in press) Studies on the
administration of human chorionic gonadotrophin to the stallion. Proceedings
of the 12th International Conference of Racing Analysts and Veterinarians,
Vancouver, Canada.
Hope that helps.
Mark
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Mark Sephton,
Planetary Sciences Research Institute,
Open University,
Milton Keynes,
MK7 6AA, UK.
Tel: + 44 (0)1908 659358
Fax: + 44 (0)1908 655910
Email: [log in to unmask]
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