Check refs by Stan Amrose, Paul Koch, Margaret Schoeninger, the Utah
group, and the South African group. Lots of work with animal models like
mice and large mammals. It's really an expansive literature, but these
are probably the best places to start learning more.
> I'm a new subscriber and was hoping someone could help answer a question.
> I'm a doctoral student in physical anthropology, and my dissertation topic
> will involve stable isotope analysis and the human skeleton. I am
> considering examining the variation in isotopic signatures at different
> locations within the skeleton, or possibly analyzing bone/teeth/hair/nails
> for isotopic signatures as indicators of geographic origin or most recent
> area of residence. One of the preliminary questions I am trying to answer
> how does the isotope, once consumed in the form of food/drinking water,
> eventually become deposited in bone? I have reviewed biology textbooks,
> isotope textbooks, several articles, and performed numerous online
> but have been unable to find specific information on the mechanism/pathway
> responsible for the incorporation of these isotopes into bone. I'd like to
> be able to describe, in detail, what happens to these isotopes once they
> enter the body and how they make it into bone. Do you have any suggestions
> on where I might look to find the answer? Thanks so much!