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MEDLIB-L  September 1995, Week 3

MEDLIB-L September 1995, Week 3

Subject:

Combination "M&M" drugs for abortion

From:

Lynne M Fox <[log in to unmask]>

Reply-To:

Medical Libraries Discussion List <[log in to unmask]>

Date:

Fri, 15 Sep 1995 15:01:44 -0600

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (119 lines)

Here's the summary of responses on the following message:
On Thu, 14 Sep 1995, Lynne M Fox wrote:
> Just the other day, (maybe it was on MEDLIB-L,) I heard of two common
> drugs, that when prescribed together could produce the same results as
> RU-486 (abortion within 24 hours.)
> Now, of course, I have a need for the names of the drugs. Can
> anyone help?
Thanks to some others who I omitted from this post because they provided the
information duplicated in the posts summarized below.
Lynne M. Fox ([log in to unmask])
James A. Michener Library Voice: 970-351-1534
University of Northern Colorado Fax: 970-351-2540
Greeley, CO 80639
 
-----------------------------------------------------------------------------
 
From [log in to unmask] Sep 15 14:42:06 1995
Subject: Abortions
The drugs are methotrexate and misoprostol. The article is in the 31 August
1995 issue of New England Journal of Medicine, page 537-540. Dosing is given.
------------------------------------------------------------------------------
From [log in to unmask] Sep 15 14:42:21 1995
Subject: M&M abortions
Two additional articles have been added to the lit on using methotrexate
and misoprostol for early abortion - Malcolm Potts: Non-surgical
abortion: Who's for methotrexate. Lancet 346:655-6, September 9, 1995
and Eric A Schaff, Steven H Elsinger, Pater Franks, Suzy S Kim: Combined
methotrexate and misoprostol for early induced abortion. Arch Fam Med
4:774-9, September, 1995. Their cites give you anything else you need.
*****************************************************************
From [log in to unmask] Sep 15 14:42:35 1995
Subject: 95.08.31--Two drugs effective at inducing abortion
I believe that the reference following my sig block is the material you
recently requested on MEDLIB.
 
Date: Fri, 15 Sep 1995 08:23:04 -0400
From: Tom Flemming <[log in to unmask]>
Subject: 95.08.31--Two drugs effective at inducing abortion /biomed/news/cita
 
Headline:
 
   Study says abortion induced with two drugs safe, effective.
 
Newspaper Article Synopsis:
   Two drugs on the market for other uses have been found to be 96% effective
   in inducing abortion in women whose pregnancies were in the first trimester.
 
Newspaper Article Source:
   Associated Press. Study says abortion induced with two drugs safe,
   effective. Star Tribune 1995 August 31:1A(col. 4-6).
 
Journal Article Citation:
   Hausknecht, R.U. Methotrexate and misoprostol to terminate early
   pregnancy. New England Journal of Medicine 1995 Aug 31;333(9):537-540.
.......................................................................
From [log in to unmask] Sep 15 14:42:55 1995
Subject: abortion drugs
I am fairly sure someone else has already responded to your question about
abortion drugs, but just in case:
methotrexate and misoprostol
 ((Baltimore) Sun 8/31/95 p.3A article reporting on a NEJM article by Richard
U. Hausknecht)
--------------------------------------------------------------------------
From [log in to unmask] Sep 15 14:43:07 1995
Subject: abortion drugs
The NYT for 8-31-95 relates that the drugs are:
First, an injection of Methotrexate, followed 5 to 7 days later by a vaginal
suppository containing Misoprostol; all in a doctor's office, and *some*
women (not many) require a second suppository treatment. Hope this helps!
PS. One of our librarians subscribes to NYT and clips & posts all the
medicbiomedical articles.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
From [log in to unmask] Sep 15 14:43:19 1995
Subject: Re: Medicines used for abortions
The article was in NEJM 333(9):537-540. Methotrexate and misoprostol to
terminate early pregnancy.
--------------------------------------------------------------------------
From [log in to unmask] Sep 15 14:43:36 1995
Subject: Re: Medicines used for abortions
The main drug is methotrexate which has been widely studied and is the
treatment of choice for ectopic pregnancies. The second drug used was
misoprostol. The announcement of this regime was made in NEJM vol.333 pgs
537-404. The very latest issue of Lancet(vol 346, Sept 9, 1995 p. 655-56)
discusses the treatment. Dosage is as follows
"methotrexate (50 mg/m2 or about 80 mg) given intramuscularly followed by
800ug of misoprostol per vagina 5-7 days later. Used 56-63 days after the
last mensstruation this regime is 88-97% effective, and before 42 days
methotrexate may be effective without misoprostol". As a statement on the
current state of the world, the author of the NEJM article made the
announcement wearing a bulletproof vest and the NEJM offices now have armed
guards. What are we coming to!
--------------------------------------------------------------------------
From [log in to unmask] Sep 15 14:43:43 1995
Subject: Re: Medicines used for abortions
Not sure if you have received your answer yet...knowing the
responsiveness of this list, I suspect you have, but just in case I
thought I would pass on this information.
On 8/31/95 the Los Angeles Times ran an article DRUG COMBINATION MAY
OFFER ABORTION OPTION : New use of substances previously approved by FDA
was 96% effective in early pregnancies, study finds. The drugs are
methotrexate, an anti-cancer drug that is toxic to fast multiplying
tissue, including fetal tissue and misoprostol, an anti-ulcer drug that
causes uterine contractions, which can expel an embryo.
The study conducted by Dr. Richard U. Hauskneehn (I think the spelling is
correct, the copy of the news article is a little blurry), anyway, the
study appreas in the 8/31/95 issue of the New England Journal of Medicine.
--------------------------------------------------------------------------
From [log in to unmask] Sep 15 14:43:59 1995
Subject: Re: Medicines used for abortions
This is Methotrexate and Misoprostol - the article is in NEJM 333(9)
August 31 p.537.
 
-------------------------------------------------------------------------
From [log in to unmask] Sep 15 14:44:26 1995
Subject: Re: Medicines used for abortions
 
The two drugs are methotrexate (by injection) followed by misoprostol (by
vaginal suppository). This is from The NY Times dated 8/31/95 (p.A1)

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November 2004, Week 4
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November 2004, Week 2
November 2004, Week 1
October 2004, Week 5
October 2004, Week 4
October 2004, Week 3
October 2004, Week 2
October 2004, Week 1
September 2004, Week 5
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September 2004, Week 3
September 2004, Week 2
September 2004, Week 1
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July 2004, Week 1
June 2004, Week 5
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June 2004, Week 1
May 2004, Week 4
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April 2004, Week 5
April 2004, Week 4
April 2004, Week 3
April 2004, Week 2
April 2004, Week 1
March 2004, Week 5
March 2004, Week 4
March 2004, Week 3
March 2004, Week 2
March 2004, Week 1
February 2004, Week 5
February 2004, Week 4
February 2004, Week 3
February 2004, Week 2
February 2004, Week 1
January 2004, Week 5
January 2004, Week 4
January 2004, Week 3
January 2004, Week 2
January 2004, Week 1
December 2003, Week 5
December 2003, Week 4
December 2003, Week 3
December 2003, Week 2
December 2003, Week 1
November 2003, Week 5
November 2003, Week 4
November 2003, Week 3
November 2003, Week 2
November 2003, Week 1
October 2003, Week 5
October 2003, Week 4
October 2003, Week 3
October 2003, Week 2
October 2003, Week 1
September 2003, Week 5
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September 2003, Week 3
September 2003, Week 2
September 2003, Week 1
August 2003, Week 5
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August 2003, Week 3
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August 2003, Week 1
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July 2003, Week 3
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July 2003, Week 1
June 2003, Week 5
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June 2003, Week 3
June 2003, Week 2
June 2003, Week 1
May 2003, Week 5
May 2003, Week 4
May 2003, Week 3
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May 2003, Week 1
April 2003, Week 5
April 2003, Week 4
April 2003, Week 3
April 2003, Week 2
April 2003, Week 1
March 2003, Week 5
March 2003, Week 4
March 2003, Week 3
March 2003, Week 2
March 2003, Week 1
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February 2003, Week 1
January 2003, Week 5
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January 2003, Week 2
January 2003, Week 1
December 2002, Week 5
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December 2002, Week 3
December 2002, Week 2
December 2002, Week 1
November 2002, Week 5
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November 2002, Week 3
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October 2002, Week 5
October 2002, Week 4
October 2002, Week 3
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September 2002, Week 5
September 2002, Week 4
September 2002, Week 3
September 2002, Week 2
September 2002, Week 1
August 2002, Week 5
August 2002, Week 4
August 2002, Week 3
August 2002, Week 2
August 2002, Week 1
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July 2002, Week 3
July 2002, Week 2
July 2002, Week 1
June 2002, Week 5
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June 2002, Week 3
June 2002, Week 2
June 2002, Week 1
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January 2002, Week 3
January 2002, Week 2
January 2002, Week 1
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December 2001, Week 3
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December 2001, Week 1
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November 2001, Week 3
November 2001, Week 2
November 2001, Week 1
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October 2001, Week 3
October 2001, Week 2
October 2001, Week 1
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September 2001, Week 4
September 2001, Week 3
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August 2001, Week 4
August 2001, Week 3
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July 2001, Week 5
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July 2001, Week 3
July 2001, Week 2
July 2001, Week 1
June 2001, Week 5
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June 2001, Week 3
June 2001, Week 2
June 2001, Week 1
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May 2001, Week 3
May 2001, Week 2
May 2001, Week 1
April 2001, Week 5
April 2001, Week 4
April 2001, Week 3
April 2001, Week 2
April 2001, Week 1
March 2001, Week 5
March 2001, Week 4
March 2001, Week 3
March 2001, Week 2
March 2001, Week 1
February 2001, Week 4
February 2001, Week 3
February 2001, Week 2
February 2001, Week 1
January 2001, Week 5
January 2001, Week 4
January 2001, Week 3
January 2001, Week 2
January 2001, Week 1
December 2000, Week 5
December 2000, Week 4
December 2000, Week 3
December 2000, Week 2
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November 2000, Week 5
November 2000, Week 4
November 2000, Week 3
November 2000, Week 2
November 2000, Week 1
October 2000, Week 5
October 2000, Week 4
October 2000, Week 3
October 2000, Week 2
October 2000, Week 1
September 2000, Week 5
September 2000, Week 4
September 2000, Week 3
September 2000, Week 2
September 2000, Week 1
August 2000, Week 5
August 2000, Week 4
August 2000, Week 3
August 2000, Week 2
August 2000, Week 1
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July 2000, Week 4
July 2000, Week 3
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June 2000, Week 5
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June 2000, Week 1
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May 2000, Week 1
April 2000, Week 5
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April 2000, Week 3
April 2000, Week 2
April 2000, Week 1
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March 2000, Week 4
March 2000, Week 3
March 2000, Week 2
March 2000, Week 1
February 2000, Week 5
February 2000, Week 4
February 2000, Week 3
February 2000, Week 2
February 2000, Week 1
January 2000, Week 5
January 2000, Week 4
January 2000, Week 3
January 2000, Week 2
January 2000, Week 1
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December 1999, Week 3
December 1999, Week 2
December 1999, Week 1
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November 1999, Week 3
November 1999, Week 2
November 1999, Week 1
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October 1999, Week 3
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October 1999, Week 1
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December 1998, Week 3
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December 1998, Week 1
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November 1998, Week 4
November 1998, Week 3
November 1998, Week 2
November 1998, Week 1
October 1998, Week 5
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October 1998, Week 3
October 1998, Week 2
October 1998, Week 1
September 1998, Week 5
September 1998, Week 4
September 1998, Week 3
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September 1998, Week 1
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July 1998, Week 3
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May 1998, Week 1
April 1998, Week 5
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April 1998, Week 3
April 1998, Week 2
April 1998, Week 1
March 1998, Week 5
March 1998, Week 4
March 1998, Week 3
March 1998, Week 2
March 1998, Week 1
February 1998, Week 4
February 1998, Week 3
February 1998, Week 2
February 1998, Week 1
January 1998, Week 5
January 1998, Week 4
January 1998, Week 3
January 1998, Week 2
January 1998, Week 1
December 1997, Week 5
December 1997, Week 4
December 1997, Week 3
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October 1997, Week 1
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September 1997, Week 2
September 1997, Week 1
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January 1997, Week 5
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April 1996, Week 3
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April 1996, Week 1
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February 1996, Week 5
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December 1995, Week 5
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April 1995, Week 1
March 1995, Week 5
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March 1995, Week 3
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February 1995, Week 4
February 1995, Week 3
February 1995, Week 2
February 1995, Week 1
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January 1995, Week 3
January 1995, Week 2
January 1995, Week 1
December 1994, Week 5
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December 1994, Week 3
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