You might want to contact Dr. Larry Needleman in the Radiology/Ultrasound Imaging Dept. at Thomas Jefferson University Medical Center in Philadelphia or Dr. John Pellerito, Chief of CT, Mri, and Vascular Laoratory at North Shore University Hospital on Long Island (516) 562-4795. Although approved possibly for echocardiography studies, I am not certain that this particular contrast agent has met with FDA approval for vascular work. Most of the contrast agents are undergoing clinical phase 1-3 trials at present for radiology and/or vascular work. I do know that Optison has been used in radiology studies for renal evaluations and looks pretty good from what I have seen.
Marsha M. Neumyer, BS, RVT
Assistant Professor of Surgery
Director Vascular Studies Section
Department of Surgery
The Pennsylvania State University College of Medicine
>>> Michel Comeaux <[log in to unmask]> 05/06 6:00 PM >>>
I have been asked by a cardiologist to perform a renal artery study on a
patient that he says is large and has poor renal functions therefore cannot
undergo angiography. He would like for me to give the patient the drug
Optison (human albumin microspheres) if I am unable to adequately visualize
the renal arteries. According to the literature, this is successfully used
during echocardiography when the outline of the heart is not adequately
visualized. It is excreted through the lungs rather than the kidneys. The
literature does not state that it works the same for visualization of the
Does anyone have any experience with or knowledge of this drug?
Michel Comeaux, RN, RVT, RDMS
Noninvasive Vascular Lab
New Iberia, La.