Hi John, Hi Janet, I would beg to differ with Antonio's recommendation in as much as my suggestion would be to un-install or at least de-activate any anti-virus programme that might be running on your 2 Isodat PCs. Also, if you can, try avoid running any other CPU intensive applications such as spread-sheets at the same time your IRMS are running and acquiring data. We've got a similar set-up here, i.e. Delta_plus_XP controlled by Isodat 2.0 (sadly no MAT252 or 253) but I couldn't say what the latest SP is. However, we don't experience any lock-up or freeze problems, which I attribute to the fact that I religiously follow the golden rule not to trust any claims made my Microsoft as to the multi-tasking capability of its various OS. If your IRMS PC is neither networked nor connected to the Internet and you are the only persons having access rights to this PC (and it's locked while you are not working on it), then running an Anti-Virus in the background is not a must. It's still good policy to scan your PC on a regular basis but don't have the Anti-Virus software running while running Isodat (or any other real-time data acquisition software). Similarly, do not run any other software packages (especially not spreadsheets or stats) while your CPU is talking to your analyzer. One missed or not completed hand-shake is all it takes for the PC to get its knickers in a twist. I'm not claiming this will solve your particular problems but it will decrease the risk of your PCs seizing up. Cheers, Wolfram ***************************************** Dr W Meier-Augenstein, CChem, MRSC Environmental Engineering Research Centre School of Civil Engineering Queen's University Belfast David Keir Building 39-123 Stranmillis Road BELFAST BT9 5AG Tel: +44 (0)28 9097 4015 (office) Tel: +44 (0)28 9097 5609 (lab) Fax: +44 (0)28 9066 3754 E-mail: <[log in to unmask]> ***************************************** Privacy & Confidentiality Notice This message is confidential and intended solely for the person(s) to whom it is addressed. It may contain privileged and confidential information. If you are not the intended recipient(s), you must not read, copy, distribute, discuss or take any action in reliance on it. If you have received this information in error, please notify the sender at <[log in to unmask]> or at one of the above telephone numbers as soon as possible. Please, also delete this message from your system. Thank you.