Beverly, Usually when I see a variance between the value of reference peaks at the start and finish of a run, it turns out to be due to water. Have you been keeping track of mass 18? Paul Eby University of Victoria >===== Original Message From Stable Isotope Geochemistry <[log in to unmask]> ===== >Greetings All, > >We have a GC (Trace/PAL)- irms (Delta Plus Advantage) with a GC III >combustion interface and have been experiencing three problems with d13C >measurements of specific compounds over the last few months. > >1. Selective loss of the low molecular weight compounds (n-alkanes < >C24) relative to the higher molecular weight compounds (n-alks> C26). >This issue has become increasingly problematic over the last few weeks, >and does NOT appear to be related to any dramatic changes in running >conditions or instrument mainetenance. Samples are injected in >splitless mode. Septa are changed every 20 injections, the inlet has >been recently re-plumbed, and flow rates are as expected through the >backflush valve (1.5 mL/minute in backflush mode) and the column (1 >mL/min). The backflush vent capillary has been replaced and is the >recommended dimension. The sample itself is fine (all peaks are as >expected and approximately equal in height) as evidenced by analysis on >a different system (GC-FID). Furthermore, there do not appear to be any >leaks in the system as checked by monitoring mass 40 under a stream of Ar. > >2. Isotopically enriched d13C values of the sample peaks (2-3 permil too >enriched, in fact). > >2. A non-systematic fractionation of +/- 1-2 permil between the first >set of CO2 ref peaks, and the last set of CO2 ref peaks on each GC run. > >Any ideas would be greatly appreciated. > >Thanks, > >Bev > >-- >~~~~~~~~~~~~~~~~~~ >Beverly Johnson >Assistant Professor >44 Campus Avenue >Department of Geology >Bates College >Lewiston, ME 04240 >ph: 207-786-6062 >fax: 207-786-8334