Dear colleagues, I was just asked by someone who is setting up a lab how feasible it is to run mostly SO2 analysis on an isotope ratio mass spec, but also some O and D in water and N and C in organic material from a EA. I don't do S analysis, but in the past my understand was that it was desirable to have a separate mass spectrometer for SO2 analysis if possible. My understanding was that SO2 would gradually affect the source and the results for O in particular but possibly other more stable compounds would deteriorate compared to a system that does not run SO2. However, with modern continuous flow systems perhaps this is not as great an issue. Any advice on this would be appreciated. Paul Brooks.