Hi, I'm preparing to make 18O/16O measurements of cellulose and bulk organic matter (leaves and wood). I've searched the isogeochem archives and I have a few questions for experienced members of the group. 1) Which reference materials? From what I understand, it's hard to keep cellulose dry and any water that it absorbs will change the 18O value. That's why the IAEA doesn't assign values for their cellulose reference material (only 13C values). For that reason, many use benzoic acid or water in silver tubes. But neither of those materials are at all close to behaving like cellulose in the combustion process. So, seems like there is no perfect answer here. I'm leaning toward VSMOW and VSLAP in silver tubes from USGS. If so, what size (0.15 uL or 0.25 uL)? 2) Working standards? I have some cellulose from Sigma. I assume this needs to be dried in a desiccator for a few days. I also read that granulated sugar from the grocery store could work. Does this need to be ground finely? 3) Sample + reference storage? Is a desiccator OK? Which kind? Glass with phosphorous pentoxide or something less hazardous? Or one of the newer plastic vacuum kind? 4) CO working tank purifying scrubs? Something to remove trace water and organics, but I can't find this thread for details right now. 5) CO working tank isotopic composition? How important is this? And how do you predict what the approximate value will be when ordering? 6) Autosampler environmental control? I suppose we could purge with He, or heat and evacuate the carousel. Pros/cons? Thanks in advance. Lisa -- ----------------------------------------- Dr. Lisa Welp, Assistant Professor Earth, Atmospheric, and Planetary Sciences Purdue University [log in to unmask] http://www.eaps.purdue.edu/research/lwelp/