Natural polymer Chitin shows great healing properties
Medical Science News
Published: Monday, 16-Jul-2007
Chitin is a polymer very common in nature as part of animals' and plants'
Only cellulose is more abundant than chitin, which makes this compound a
highly important renewable resource that can easily be found in arthropods,
insects, arachnids, molluscs, fungus and algae.
The fishing industry in Cuba generates great amounts of lobster waste,
"a pollutant rich in proteins and chitin", states Professor Carlos Andrés
Peniche Covas, head of the Biopolymers Research Group, from the Biomaterials
Centre of the University of Havana. This group is doing research into chitin
and chitosan extraction from such waste, in collaboration with the Spanish
Centre for Scientific Research (CSIC), the Complutense University in Madrid
(Spain) and the Mexican Research Centre for Food and Development.
Prof. Peniche points out that "this work allows for the first accurate and
comprehensive results of a university study on chitin and chitosan. The
study starts at the extraction of these compounds from polluting waste of
the Cuban fishing industry and it goes on to cover these products'
characterisation through traditional techniques and some more innovative
ones, the study of their properties, the development of new by-products and
the testing of their practical applications in areas useful for this
Caribbean country, such as agriculture and biomedicine."
Use in medicine
These researchers' work has led to the development of a procedure to obtain
surgical materials with great healing and antiseptic properties. "This
procedure involves using chitosan to cover surgical threads and lint, into
which antibiotics are injected. By doing this, we obtain medical materials
with both antimicrobial and healing properties and, as they are covered in a
natural polymer, with a higher degree of biocompatibility." Research shows
that such properties remained unmodified after sterilisation.
Two new types of surgical thread were produced in collaboration with the
Cuban Superior Institute of Military Medicine "Dr. Luis D? Soto": Agasut-Q,
covered with chitosan (healing properties) and Agasut-QE, covered with
chitosan and streptomycin (healing and antimicrobial properties). After
preclinical and clinical trials were approved, both surgical thread types
were introduced and successfully used in several Cuban hospitals.
Use in agriculture
The study, however, was not restricted to biomedicine. In cooperation with
the Cuban National Centre for Agricultural and Livestock Health (CENSA),
this group worked in "seed coating to boost farming yields as well as in
encapsulation of somatic embryos to design artificial seeds".
In trials, tomato seeds of variety 1-17 were coated with chitosan.
Under laboratory conditions, treated seeds showed significantly higher
growth speed and percentage of successful germination when compared to
In Prof. Peniche's words, the research group concluded that "chitosan works
as a bio-stimulant in tomato seed treatment by producing better seed
germination and greater plant height, stem thickness and dry mass about a
week earlier than usual". Chitosan proved to be a natural polymer with great
film-generating capacity, apart from other highly interesting properties:
chitosan does not produce polluting substances, it is non-toxic and