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There was a front page story in today's edition of "Canada's national
newspaper" _The Globe and Mail_ entitled: "Fat-melting hormone poised for
human tests".
 
The following quotations really capture the imagination:
 
        "Obese mice treated in laboratory studies with the OB protein, which
        behaves like a hormone, lost 20 to 40 per cent of their body
        weight in 30 days, with no side effects."
 
        "...  The company that holds the patent on a genetic product it calls
        "leptin" hopes to begin safety testing on humans next year.  ..."
 
        "So far, it appears that the treatment would have to be given by
        daily injection or from an implant.  If the OB protein were taken
        in pill form, it would be digested in the stomach before it
        reached the bloodstream, and it wouldn't work."
 
The only names given in the story are those of Dr. Frank Collins, "who led
a research team at Amgen, Inc., of Thousand Oaks, Calif."  and the firm
of Lehman Brothers in New York, which broke an embargo on the release of
the findings by divulging an analyst's report on the commercial prospects
of the information.
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Tom Flemming                    Internet: [log in to unmask]
Health Sciences Library         Ariel: 130.113.181.186
McMaster University             Voice: (905) 525-9140  x22321
1200 Main Street West           Fax:   (905) 528-3733
Hamilton, ON   L8N 3Z5
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