One of the ways of dealing with a question of this sort, since I assume that Metacresol is an ingredient used in the preparation of commercially available insulin, is to contact the manufacturer of the product. They should have an MSDS (material safety data sheet) on the chemical ingredients in the commercial product they make available since their workers are exposed to it during manufacture of the insulin. This should give basic information on the known hazards from the chemical. Allergic reactions are usually covered in MSDS. Some collection of MSDS are available for searching free of charge on the 'net, but none that I have searched yet includes Metacresol. ..................................................................... Tom Flemming Internet: [log in to unmask] Health Sciences Library Ariel: 130.113.181.186 McMaster University Voice: (905) 525-9140 x22321 1200 Main Street West Fax: (905) 528-3733 Hamilton, ON L8N 3Z5 Visit the _Health Care Information Resources_ page URL http://www-hsl.mcmaster.ca/tomflem/top.html ....................................................................... On Tue, 20 Feb 1996, Leeila Bina wrote: > A library patron is interested in information on allergic reactions to > Metacresol (a preservative used in insulin) and how it is treated. Has > anyone in Internet land seen anything on this? We did a MEDLINE search but > did not find anything useful for the patron. Thank you in advance for any > help. Please > send responses to: > > Leeila Bina > [log in to unmask] > > Q&R Medcenter One Health Sciences Library > 622 Ave. A EAst > Bismarck, ND 58501 > 701-222-5390 >