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One of the ways of dealing with a question of this sort, since I
assume that Metacresol is an ingredient used in the preparation of
commercially available insulin, is to contact the manufacturer of the
product.
 
They should have an MSDS (material safety data sheet) on the
chemical ingredients in the commercial product they make available since
their workers are exposed to it during manufacture of the insulin.  This
should give basic information on the known hazards from the chemical.
Allergic reactions are usually covered in MSDS.
 
Some collection of MSDS are available for searching free of charge on the
'net, but none that I have searched yet includes Metacresol.
.....................................................................
Tom Flemming                    Internet: [log in to unmask]
Health Sciences Library         Ariel: 130.113.181.186
McMaster University             Voice: (905) 525-9140  x22321
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Hamilton, ON   L8N 3Z5
 
 
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.......................................................................
 
On Tue, 20 Feb 1996, Leeila Bina wrote:
 
> A library patron is interested in information on allergic reactions to
> Metacresol (a preservative used in insulin) and how it is treated.  Has
> anyone in Internet land seen anything on this?  We did a MEDLINE search but
> did not find anything useful for the patron.  Thank you in advance for any
> help.  Please
> send responses to:
>
> Leeila Bina
> [log in to unmask]
>
> Q&R Medcenter One Health Sciences Library
> 622 Ave. A EAst
> Bismarck, ND  58501
> 701-222-5390
>